IMPROVING PATIENT COMFORT
WITH NEXT GENERATION
CONTACT LENSES
We are working on the next-generation of contact lenses capable of delivering drug effectively to the front of the eye to treat anterior ocular conditions. We are also improving upon the formulation of contact lenses to improve patient comfort. Working with industry partners, we are helping formulations reach market fast.
DELIVERING VISION SAVING THERAPEUTICS TO HARD TO REACH OCULAR TISSUE
Utilizing our expertise in drug delivery, we are developing novel methods for sustained drug delivery to ocular tissues through our patented technologies and biomedical modelling strategies.
DESIGNING NOVEL POLYMER BIOMATERIALS FOR OCULAR APPLICATION
As Chemical Engineers, polymer chemistry is in our blood. Our vast knowledge allows us to design and synthesize original formulations that can prolong ocular residence time, increase tissue permeation, and deliver that vital cargo to where it needs to go.
Liu L, Rambarran T, Muirhead B, Lasowski F, Sheardown H. A radiolabeling method for precise quantification of polymers. Bioconj Chem. 33:634-42 (2022).
CREATING ANIMAL MODELS TO BETTER OUR UNDERSTANDING OF OCULAR PATHOLOGIES
Our expertise in animal modeling allows us to study a breadth of ocular disease states as well as test our novel ocular biomaterials in-vivo.
Capabilities:
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Imaging Techniques
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Posterior Fundus​
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Posterior Optical Coherence Tomography (OCT)
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Posterior Fluorescein Angiography
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Anterior Slit Lamp
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Anterior OCT
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Metrics
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Tear Osmolarity​
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Tear Volume
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Ocular Surface Staining
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Histology
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ACADEMIC COLLABORATIONS
Sheardown Lab is actively collaborating with many academic partners, including other researchers at McMaster University and the University of Waterloo. For further information on opportunities for collaboration and fees for service work, please refer to the C20/20 Innovation Hub.